Detailed Summary of Rice Bran Arabinoxylan Compound (RBAC) It is an undeniable fact that maintaining a strong, vital immune system is a key component of good health, high quality of life and longevity. However many factors can suppress immune function. These factors include, stress, pollution, insufficient rest, heredity, aging, exposure to toxins, medications and poor diet. Due to our hectic lifestyles and abundantly available nutrition depleted preservative laden food, it is difficult to obtain all the nutrients necessary for our body and immune system to operate at peak level. Development of RBAC The developers of RBAC married their knowledge of Japanese nutritional foods with the latest biotechnology to produce a natural product intended to enhance the immune system and protect it from being weakened and therefore more susceptible to successful attacks from antigens. It has been known for many years that certain large polysaccharide molecules, complex carbohydrates, may enhance immunity. Unfortunately, these polysaccharides (most are fibers) are not easily absorbed because of their large molecular structure. The developers of RBAC originally produced a lower molecular weight polysaccharide from mushrooms and it proved to have immune enhancing capabilities. However, the researchers were not happy with the batch to batch consistency of the product and the level of immune enhancement it provided, so development efforts continued. Rice Bran is known to have nutritional value but it is not well absorbed. It contains cellulose, several types of hemicellulose, pectin and lignin, all of which are large molecules. One type of hemicellulose, hemicellulose B, a complex polysaccharide, is documented to have immunomodulatory properties and can be extracted from rice bran with water. However, due to its large molecular weight it is not readily absorbed by the body. Research was directed at attempting to reduce the molecular size of hemicellulose B while maintaining the same chemical functionality, arabinoxylan, to preserve it immune modulating properties. The researchers looked to enzymes as the tool to reduce the molecular size in a precise manner. A specific enzyme complex from Shitake mushroom was found to selectively cut certain chemical bonds to reduce the molecular weight but not break the bonds necessary to keep the arabinoxylan functionality. What is RBAC? Hemicellulose B, a water soluble extract of rice bran is reacted with an enzyme complex extracted from Shitake mushroom. The enzyme is used as a natural scissor that “cuts” the large hemicellulose B molecule, producing a smaller molecule that is more bio-available but still has the key chemical functional groups that provide the immune enhancing benefits. The enzyme complex selectively breaks some chemical bonds but not others. The process, which takes two weeks, is patented. A major benefit of the process is that the batch to batch inconsistency that is usually associated with natural products is eliminated, resulting in a product that is very consistent in performance. A word of caution - arabinoxylan exists in several grains. However, these arabinoxylan compounds have much higher molecular weights than Rice Bran Arabinoxylan Compound. Thus, their immunomodulating impact is much less because they are significantly less bio-available. Benefits of RBAC RBAC is an immune modulator. This means it has the ability to increase the strength of a compromised immune system and bring an over stimulated one into balance. This is not very common, while there are many products available that are marketed as immune enhancers, very few are immune modulators and even fewer are supported by clinical studies. The research studies on RBAC provide evidence of its immunomodulating capabilities. The fact that RBAC does not cause over stimulation of the immune system results in another benefit. It can be used for prolonged periods of time without causing the immune system to become overly aggressive and attack the body, unlike some other immune enhancers. RBAC also does not lose effectiveness with long term use as experienced with many other immune products. RBAC works fast, human studies show that when taken at the recommended dosage, it has an impact on the immune system within several weeks. For specific health concerns a “loading” dose is recommended. This dosage, 3 g/day, increases the immune system to peak performance in weeks. After four weeks the dose is reduced to a maintenance level of 1 g/day. This is another significant difference from other immune products. How does RBAC work? The clinical studies on Rice Bran Arabinoxylan Compound suggest that it has a number of modes of activity on the
immune system. On average, RBAC increases Natural Killer cell (NK cell) activity by 300% while increasing the proliferation of T & B cells by
250% and 200% respectively. It increases both cytotoxic and helper T cells. NK, T and B cells are white blood cells. Cytotoxic T cells destroy
targeted abnormal cells. Helper T cells serve to call for the production of more B cells and cytotoxic T cells. B cells mature in the bone. They
synthesize multiple antibodies specific to different antigens. The antibodies are sent into the blood stream to seek and destroy the specific
antigen for which they were made. An advantage of antibodies is that they reproduce in the blood long term and have a memory that allows them to
be prepared the next time the antigen is present. Antibodies react more quickly and aggressively when an antigen presents itself for the second
time. Powerful Natural Antioxidant RBAC has also been shown to have anti-inflammatory and anti-oxidant properties. More and more studies indicate a
correlation between inflammation and diseases. Inflammation is now thought to be among the causative factors for cancer and heart disease. The
damage caused by free radicals at the cellular level is well documented. A research study with RBAC successfully illustrated its ability to act
as an anti-oxidant.
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